From Chapter 1:
The only mention made of tobacco by Raleigh himself occurs in a testamentary note made a little while before his execution in 1618. Referring to the tobacco remaining on his ship after his last voyage, he wrote: "Sir Lewis Stukely sold all the tobacco at Plimouth of which, for the most part of it, I gave him a fift part of it, as also a role for my Lord Admirall and a role for himself ... I desire that hee may give his account for the tobacco." As showing how closely Sir Walter's name was associated with it long after his death, Dr. Brushfield quotes the following entry from the diary of the great Earl of Cork: "Sept. 1, 1641. Sent by Travers to my infirme cozen Roger Vaghan, a pott of Sir Walter Raleighes tobackoe."

From Chapter 8:
All's well that ends well; but one cannot help wondering what kind of tobacco it was that the Birmingham tradesman used, a half pipeful of which had such a deadly effect—but perhaps the effect was due to the salt, not to the tobacco.
In the year after that which witnessed Coleridge's adventure, i.e. in 1796, a tobacco-box with a history was the subject of a legal decision. This box, made of common horn and small enough to be carried in the pocket, was bought for fourpence by an overseer of the poor in the time of Queen Anne, and was presented by him in 1713 to the Society of Past Overseers of the parish of St. Margaret, Westminster. In 1720 the Society, in memory of the donor, ornamented the lid with a silver rim; and at intervals thereafter additions were made to an extraordinary extent to the box and its casings. Hogarth engraved within the lid in 1746 a bust of the victor of Culloden. Gradually the horn box was enshrined within one case after another—usually silver lined with velvet—each case bearing inscribed plates commemorating persons or events. A Past Overseer who detained the box in 1793 had to give it back after three years of litigation. A case of octagon shape records the triumph of Justice, and Lord Chancellor Loughborough pronouncing his decree for the restitution of the box on March 5, 1796. In later days many and various additions have been made to the many coverings of the box, recording public events of interest.